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Motivation of NiMOdb


    Tobacco (Nicotiana tabacum) is not only one of the most widely studied plant species in fundamental research but also an economically significant crop. It serves as an excellent model organism for plant biology studies due to its relatively large genome size, well-established transformation techniques, and rapid growth rate. Research on tobacco has led to important insights into various aspects of plant molecular biology, such as photosynthesis, plant-pathogen interactions, and secondary metabolite biosynthesis.
    With the development of high-throughput sequencing technologies, a large amount of genomic, transcriptomic, and proteomic data related to tobacco has been generated. However, these data are currently scattered across different platforms and studies, making it difficult for researchers to comprehensively access and analyze them. In addition, functional genomics research on tobacco aims to understand the functions of genes, their regulatory mechanisms, and their roles in various biological processes. To date, there is a lack of an integrated resource that can efficiently integrate these data and support in-depth functional genomics studies.
   To fill this gap and meet the increasing demands of the tobacco research community, we have developed NiMOdb. This is a comprehensive database that integrates diverse data related to tobacco functional genomics. It includes information on gene sequences, gene expression profiles across different tissues and developmental stages, gene knockout/down phenotypes, and regulatory elements. By incorporating multiple annotations such as “tissue”, “developmental stage”, “gene function”, “knockout/down methods”, and “expression changes”, NiMOdb provides putative functional information for different tobacco genes. The database also offers user-friendly search and analysis tools, enabling researchers to easily retrieve relevant data, explore gene-gene relationships, and conduct functional genomics research. In summary, NiMOdb is set to become an essential resource for researchers engaged in tobacco functional genomics studies.

Workflow of NiMOdb


NiMOdb is an integrated resource for tobacco functional genomics.

workflow picture